Historical project context

This page is about the former AIDA research project (2011–2017). It does not describe current activity or endorsement of this independent website.

At a glance

  • Historical period: December 2011–November 2017.
  • Programme: FP7-HEALTH; CORDIS project ID 278348.
  • Research combined clinical trials, microbiology and pharmacology.
  • This independent educational website is not the former consortium.

Why older antibiotics were studied

Some older medicines were developed before today’s standard approaches to clinical evaluation. With resistance increasing and limited new options available, the project examined whether existing treatments could be better understood through modern clinical research.

The project focused on five off-patent medicines: colistin, fosfomycin, nitrofurantoin, minocycline and rifampicin. These names are historical research subjects, not suggestions for treatment.

Clinical research and work packages

According to CORDIS, three randomised clinical trial areas compared colistin-based approaches for severe resistant infections; fosfomycin and nitrofurantoin for lower urinary tract infections; and a minocycline/rifampicin approach with another treatment for complicated skin and soft-tissue infections.

Alongside the trials, the consortium planned pharmacokinetic, pharmacodynamic and microbiological work, and activities to share findings. These components were organised as work packages. The exact results and publications should be read at their original sources, not inferred from the original study plan.

Why preserve this page?

Existing links to the former website deserve an accurate historical destination. We preserve the subject and the project’s dates, while keeping it separate from the consumer-focused site that now uses this domain.

For a plain-language introduction to today’s antibiotic questions, see our guides on how spectrum works and why resistance matters.

Sources

Original references
  1. European Commission CORDIS · AIDA project record (278348)
  2. European Commission CORDIS · AIDA results
  3. European Commission CORDIS · Old antibiotics – a new lease of life

These sources informed this overview. Their organisations do not endorse or review this website.

This page is for general education only. It does not replace advice from a doctor, pharmacist or other qualified healthcare professional. Read our medical disclaimer.